Oral immunotherapy with boiled peanuts could help peanut allergic children

Oral immunotherapy with boiled peanuts could help peanut allergic children

  • 08 February 2023
  • Research

A new Australian study has added to the growing body of research looking at the use of boiled peanuts in oral immunotherapy (OIT) to treat peanut allergy. 

The clinical trial aimed to assess the efficacy and safety of OIT using doses of boiled peanuts followed by roasted peanuts for treating peanut allergy in children. 

Between 1 July 2017 and 22 June 2018, 70 participants aged 6-18 years with peanut allergy were enrolled on the study. They underwent OIT involving sequential up-dosing with 12-hour boiled peanut for 12 weeks, 20 hour boiled peanut for 20 weeks and roasted peanut for 20 weeks, to a target maintenance dose of 12 roasted peanuts daily. Desensitisation was successfully induced in 80% of participants (56 of 70). 

The trial concluded that OIT using boiled followed by roasted peanuts appeared “effective in inducing desensitization and is associated with a favourable safety profile.” 

Read the full article on Wiley Online Library