Following on from media reports last week commenting on issues with the supply of EpiPen® (Senior) Adrenaline Auto-Injector in the UK, the Anaphylaxis Campaign have contacted Mylan who distribute EpiPen® in the UK for further updates. Mylan have provided us with a statement, which is below.
Our advice remains during this time to check the expiry date on your Adrenaline Auto-Injectors and get a repeat prescription from your GP well in advance. Your AAI devices will have instructions for use printed on the outside and generally will have a shelf life of up to 18 months. The expiry date will be printed on the casing.
If you are worried about your prescription, we advise you to visit your GP and discuss this directly with them. Your GP can prescribe an alternative medication if required. The AAI devices prescribed in the UK at present are Emerade®, EpiPen® and Jext®.
If you are prescribed an alternative AAI device, ensure that you know how to use it. The place where adrenaline is administered is the same for all three injectors (the muscle in the front quarter of the outer thigh) but the method of administration for each AAI varies slightly. Training should be given to all those who might be required to administer your adrenaline in an emergency, such as family members and friends.
We advise you not to dispose of any ‘expired’ AAI devices before you have obtained a new device. The adrenaline solution in your device should be clear and colourless. If the liquid in your device is not cloudy or discoloured, the AAI device can still be used in an emergency.
We advise you to continue to always carry your AAIs with you and follow your usual risk management techniques to avoid your allergen and reduce the likelihood that you will experience a severe allergic reaction and need to use your adrenaline.
The pharmaceutical companies who distribute AAIs have their own customer care departments and formal complaints procedures. If you have any concerns we encourage feedback to be given directly to the organisations responsible. Please speak to Mylan customer services in the first instance on +44 (0)1707 853 100.
You can also contact our helpline and information team at firstname.lastname@example.org or call 01252 542 029 for support between Monday-Friday, 9am-5pm.
Statement from Mylan
Availability of EpiPen® 0.3mg Adrenaline Auto-Injector
Due to manufacturing delays from our contract manufacturer, Meridian Medical Technologies, a Pfizer company, there are intermittent supply constraints of EpiPen® 0.3mg Adrenaline Auto-Injector in the UK.
Latest Supply Status
Distribution of EpiPen 0.3mg Adrenaline Auto-Injector from Pfizer to our distribution partner and onwards to pharmacies in the UK will continue as shipments arrive. The next shipment is expected to be delivered to the warehouse of our UK distribution partner toward the end of April 2018. The product will then be immediately shipped to pharmacies. Until this next shipment arrives, EpiPen 0.3mg Adrenaline Auto-Injectors may not be available.
With patient access as our priority, we will continue to proactively and diligently update pharmacies, healthcare professionals and patient advocacy groups across the country regarding any changes in stock availability.
NOTE: At this time, there are no supply constraints of EpiPen Jr® 0.15mg Adrenaline Auto-Injectors.
Ongoing Supply Management
Mylan is working closely with Pfizer to manage supply carefully to avoid long-term supply shortages. Pfizer anticipates that production rates will increase over the coming months; however, at this time, cannot commit to a specific time for when the supply constraint will be fully resolved. We are confident in the safety and efficacy of the EpiPen® products being produced at Pfizer’s site and are working closely with them to alleviate the situation and achieve a steady state of supply as expeditiously as possible.
Information for Patients
Mylan is unable to make any specific treatment recommendation to individual patients. Patients should speak to their healthcare provider for appropriate actions to be taken.
Information for Prescribers
Please note, when validating the expiry date of an adrenaline auto-injector, the product expires on the last day of the month indicated. For example, if it expires in April, it remains valid (not expired) until April 30.
If you require additional information or have any questions, please contact +44(0) 1707 853 100.